| League | Date | Home Team | Score | Away Team |
|---|---|---|---|---|
| PL | 22-05-2022 | Norwich | 0 - 5 | Tottenham |
| PL | 15-05-2022 | Tottenham | 1 - 0 | Burnley |
| PL | 12-05-2022 | Tottenham | 3 - 0 | Arsenal |
| PL | 07-05-2022 | Liverpool | 1 - 1 | Tottenham |
| PL | 01-05-2022 | Tottenham | 3 - 1 | Leicester |
| PL | 23-04-2022 | Brentford | 0 - 0 | Tottenham |
| PL | 16-04-2022 | Tottenham | 0 - 1 | Brighton |
| PL | 09-04-2022 | Aston Villa | 0 - 4 | Tottenham |
| PL | 03-04-2022 | Tottenham | 5 - 1 | Newcastle |
| PL | 20-03-2022 | Tottenham | 3 - 1 | West Ham |
| PL | 16-03-2022 | Brighton | 0 - 2 | Tottenham |
| PL | 12-03-2022 | Man United | 3 - 2 | Tottenham |
| PL | 07-03-2022 | Tottenham | 5 - 0 | Everton |
| PL | 26-02-2022 | Leeds | 0 - 4 | Tottenham |
| PL | 23-02-2022 | Burnley | 1 - 0 | Tottenham |
| PL | 19-02-2022 | Man City | 2 - 3 | Tottenham |
| PL | 13-02-2022 | Tottenham | 0 - 2 | Wolves |
| PL | 09-02-2022 | Tottenham | 2 - 3 | Southampton |
| PL | 23-01-2022 | Chelsea | 2 - 0 | Tottenham |
| PL | 19-01-2022 | Leicester | 2 - 3 | Tottenham |
| PL | 01-01-2022 | Watford | 0 - 1 | Tottenham |
| PL | 28-12-2021 | Southampton | 1 - 1 | Tottenham |
| PL | 26-12-2021 | Tottenham | 3 - 0 | Crystal Palace |
| PL | 19-12-2021 | Tottenham | 2 - 2 | Liverpool |
| PL | 05-12-2021 | Tottenham | 3 - 0 | Norwich |
| PL | 02-12-2021 | Tottenham | 2 - 0 | Brentford |
| PL | 21-11-2021 | Tottenham | 2 - 1 | Leeds |
| PL | 07-11-2021 | Everton | 0 - 0 | Tottenham |
| PL | 30-10-2021 | Tottenham | 0 - 3 | Man United |
| PL | 24-10-2021 | West Ham | 1 - 0 | Tottenham |
| PL | 17-10-2021 | Newcastle | 2 - 3 | Tottenham |
| PL | 03-10-2021 | Tottenham | 2 - 1 | Aston Villa |
| PL | 26-09-2021 | Arsenal | 3 - 1 | Tottenham |
| PL | 19-09-2021 | Tottenham | 0 - 3 | Chelsea |
| PL | 11-09-2021 | Crystal Palace | 3 - 0 | Tottenham |
| PL | 29-08-2021 | Tottenham | 1 - 0 | Watford |
| PL | 22-08-2021 | Wolves | 0 - 1 | Tottenham |
| PL | 15-08-2021 | Tottenham | 1 - 0 | Man City |