| League | Date | Home Team | Score | Away Team |
|---|---|---|---|---|
| CH | 08-05-2021 | Notts Forest | 1 - 2 | Preston |
| CH | 01-05-2021 | Preston | 2 - 0 | Barnsley |
| CH | 24-04-2021 | Coventry | 0 - 1 | Preston |
| CH | 20-04-2021 | Preston | 3 - 0 | Derby |
| CH | 17-04-2021 | Stoke | 0 - 0 | Preston |
| CH | 10-04-2021 | Preston | 0 - 5 | Brentford |
| CH | 05-04-2021 | Swansea | 0 - 1 | Preston |
| CH | 02-04-2021 | Preston | 1 - 1 | Norwich |
| CH | 20-03-2021 | Preston | 0 - 1 | Luton |
| CH | 16-03-2021 | Middlesbrough | 2 - 0 | Preston |
| CH | 13-03-2021 | Wycombe | 1 - 0 | Preston |
| CH | 06-03-2021 | Preston | 1 - 1 | Bournemouth |
| CH | 02-03-2021 | Millwall | 2 - 1 | Preston |
| CH | 27-02-2021 | Preston | 3 - 0 | Huddersfield |
| CH | 24-02-2021 | Preston | 0 - 0 | QPR |
| CH | 20-02-2021 | Cardiff | 4 - 0 | Preston |
| CH | 16-02-2021 | Preston | 0 - 1 | Watford |
| CH | 12-02-2021 | Blackburn | 1 - 2 | Preston |
| CH | 06-02-2021 | Preston | 1 - 2 | Rotherham |
| CH | 30-01-2021 | Sheffield Weds | 1 - 0 | Preston |
| CH | 24-01-2021 | Preston | 0 - 0 | Reading |
| CH | 20-01-2021 | Birmingham | 0 - 1 | Preston |
| CH | 16-01-2021 | Bristol City | 2 - 0 | Preston |
| CH | 02-01-2021 | Preston | 0 - 1 | Notts Forest |
| CH | 29-12-2020 | Preston | 2 - 0 | Coventry |
| CH | 26-12-2020 | Derby | 0 - 1 | Preston |
| CH | 18-12-2020 | Preston | 1 - 0 | Bristol City |
| CH | 15-12-2020 | Barnsley | 2 - 1 | Preston |
| CH | 12-12-2020 | Luton | 3 - 0 | Preston |
| CH | 09-12-2020 | Preston | 3 - 0 | Middlesbrough |
| CH | 05-12-2020 | Preston | 2 - 2 | Wycombe |
| CH | 01-12-2020 | Bournemouth | 2 - 3 | Preston |
| CH | 28-11-2020 | Watford | 4 - 1 | Preston |
| CH | 24-11-2020 | Preston | 0 - 3 | Blackburn |
| CH | 21-11-2020 | Preston | 1 - 0 | Sheffield Weds |
| CH | 07-11-2020 | Rotherham | 2 - 1 | Preston |
| CH | 04-11-2020 | Reading | 0 - 3 | Preston |
| CH | 31-10-2020 | Preston | 1 - 2 | Birmingham |
| CH | 28-10-2020 | Preston | 0 - 2 | Millwall |
| CH | 24-10-2020 | Huddersfield | 1 - 2 | Preston |
| CH | 21-10-2020 | QPR | 0 - 2 | Preston |
| CH | 18-10-2020 | Preston | 0 - 1 | Cardiff |
| CH | 04-10-2020 | Brentford | 2 - 4 | Preston |
| CH | 26-09-2020 | Preston | 0 - 1 | Stoke |
| CH | 19-09-2020 | Norwich | 2 - 2 | Preston |
| CH | 12-09-2020 | Preston | 0 - 1 | Swansea |